Mental health & addiction

Neurons inside human brain

Synapse-restoring pill set for human trials as novel schizophrenia treatment

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Spinogenix is the American company behind the once-a-day pill that restored lost nerve cell connections in people with amyotrophic lateral sclerosis (ALS). Having been granted approval from the Australia Human Research Ethics Committee (HREC), it is now actively enrolling participants for its Phase 2 clinical trial to evaluate the safety, effectiveness, tolerability, and pharmacodynamics of once-a-day SPG302 as a treatment for schizophrenia.

Naloxone and Narcan

U.S. overdose deaths plummet, saving thousands of lives

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For the first time in decades, public health data shows a sudden and hopeful drop in drug overdose deaths across the U.S. National surveys compiled by the Centers for Disease Control and Prevention already show an unprecedented decline in drug deaths of roughly 10.6% last year. That’s a huge reversal from recent years when fatal overdoses regularly increased by double-digit percentages.

MIT naloxone sensor implant

MIT scientists reverse opioid overdoses with ‘Narcan sensor’ implanted under skin

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In 2023, more than 100,000 Americans died from opioid overdoses. The most effective way to save someone who has overdosed is to administer a drug called naloxone, but help can’t always reach the person in time. Researchers at MIT and Brigham and Women’s Hospital have developed a new device to address this problem. The device, about the size of a stick of gum, can be implanted under the skin. When it determines that an overdose has occurred, it rapidly pumps out a dose of naloxone.

px Fentanyl mg A lethal dose in most people

New sensor is six orders of magnitude more sensitive than any electrochemical sensor for the deadly drug

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Synthetic opioids are one of the main drivers in overdose deaths in the United States. They are often mixed with other drugs, but because of their potency, they are often present in such small amounts that they can be hard to detect. The new sensor, developed by researchers at the University of Pittsburgh, uses carbon nanotubes and gold nanoparticles to tell the most deadly drugs apart from others.

Banisteriopsis caapi vine

Church of the Eagle and the Condor can now drink ayahuasca legally in the U.S.

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Ayahuasca is a psychoactive brew traditionally used by Indigenous cultures in the Amazon and Orinoco. It is now often used to help treat depression, PTSD, trauma, and other mental illnesses and to promote spiritual and emotional development. The Church of the Eagle and the Condor is officially the first non-Christian church in the U.S to obtain legal protections to use it as a sacrament.

Golden Gate Bridge

Suicide-prevention net beneath Golden Gate Bridge completed

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A long-awaited suicide prevention barrier at the Golden Gate Bridge has been completed, marking the culmination of a tireless campaign by families who lost loved ones at the famous structure. Crews had been working to finish installing stainless steel nets on both sides of the bridge before a promised 2024 deadline.

Woman crying

New California law allows employee leave for pregnancy loss

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A new law that allows parents who experience a reproductive loss, such as miscarriage and stillbirth, to take leave from work will go into effect in California in 2024. The right to utilize reproductive loss leave applies to any person who would have been a parent if the loss had not occurred.

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