Technology & innovation

Close-up depiction of a microorganism

Breakthrough genomic test identifies virtually any infection in one go

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Researchers at University of California San Francisco (UCSF) have developed a single genomic test that can quickly detect virtually any kind of pathogen in a patient. This allows for much quicker diagnoses, enables targeted treatment to begin sooner, and could lower healthcare costs. Over the course of 7 years, researchers led by UCSF professor Charles Chiu tested 4,828 patients’ samples with its clinical mNGS method. The mNGS test accurately identified 86% of neurological infections.

Human eye up close

Japanese researchers develop world-first stem-cell treatment that restores vision in humans

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Kohji Nishida, an ophthalmologist at Osaka University in Japan, and his colleagues used an alternative source of cells — induced pluripotent stem (iPS) cells — to make the corneal transplants. They took blood cells from a healthy donor and reprogrammed them into an embryonic-like state, then transformed them into a thin, transparent sheet of cobblestone-shaped corneal epithelial cells. After the transplants, all four recipients showed immediate improvements in their vision and a reduction in the area of the cornea affected by limbal stem-cell deficiency. The improvements persisted in all but one recipient, who showed slight reversals during a one-year observation period.

Landmine

Groundbreaking laser tech enables faster, safer landmine detection

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Researchers at the University of Mississippi have come up with a faster, more efficient method for detecting landmines – millions of which pose a lethal threat to people in war-ravaged countries all over the world. That could spell a safer future for people who live in 70 current and former war-torn countries around the world that are riddled with an estimated 110 million active landmines. These explosives caused 2,793 deaths globally in 2017, and that number tragically rose to 4,710 in 2022.

Wooden satellite

World’s first wooden satellite, developed in Japan, heads to space

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LignoSat, developed by Kyoto University and homebuilder Sumitomo Forestry, opens new tab, will be flown to the International Space Station on a SpaceX mission, and later released into orbit about 250 miles above the Earth. Named after the Latin word for “wood”, the palm-sized LignoSat is tasked to demonstrate the cosmic potential of the renewable material as humans explore living in space. Decommissioned satellites must re-enter the atmosphere to avoid becoming space debris. Conventional metal satellites create aluminum oxide particles during re-entry, but wooden ones would just burn up with less pollution.

Holding turmeric-like substance in front of Berkeley's Campanile

U.C. Berkeley researchers use turmeric-like powder to ‘clean the air entirely’ of carbon dioxide

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New research from U.C. Berkeley, published in Nature, points to a new material – a bright yellow powder that resembles turmeric – that could help rid the air all around us of CO2. The scientists say that just 200 grams of the material can absorb up to 20 kilograms of carbon in a year – which is approximately the same absorption potential as a tree. The substance could be easily integrated into carbon capture systems already deployed to remove CO2 from refinery emissions or to capture atmospheric carbon and store it underground.

Blood cells under microscope

Danish scientists design new form of insulin that automatically switches itself on and off

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For decades, researchers have been working to develop a system that can automatically adjust insulin activity based on the amount of glucose in a person’s blood. Now, Rita Slaaby, a principal scientist at pharmaceutical company Novo Nordisk in Bagsværd, Denmark, and her colleagues engineered an insulin molecule with a switch that turns its activity on and off in response to glucose levels in the blood. In animals, this ‘smart’ insulin reduces high blood-sugar concentrations effectively while preventing levels from dropping too low.

Insulin pens

New treatment eliminates insulin for 86% of patients in early trials

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New research from Amsterdam University Medical Center introduces a promising new treatment approach for type 2 diabetes (T2D) that has the potential to greatly reduce or even eliminate the need for insulin therapy. This innovative approach, which combines a novel procedure known as ReCET (Re-Cellularization via Electroporation Therapy) with semaglutide, resulted in the elimination of insulin therapy for 86% of the 14 patients participating in initial trials. Globally, T2D affects 422 million people. While insulin therapy is commonly used to manage blood sugar levels in T2D patients, it can result in side effects such as weight gain and further complicate diabetes management.

Man clutching his chest from acute pain

New heart attack detector gives results in minutes, not hours

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Someone presenting to the emergency room with a suspected heart attack will undergo a number of standard blood tests to determine heart muscle damage. The problem is that it can take one or two hours to receive the results. Now, Johns Hopkins University researchers have led the design of a tiny chip that diagnoses heart attack by detecting these important biomarkers in minutes rather than hours, even if they are present at very low concentrations. The researchers foresee an at-home heart attack detector in the future.

Ovarian and Cervical Cancer Awareness. a Teal Ribbon

New cervical cancer treatment regime ‘cuts risk of dying from disease by 40%’

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Doctors are hailing a “remarkable” new treatment regime for cervical cancer developed by researchers at University College London that reduces the risk of dying by 40%, in the biggest advance against the disease in 25 years. The new treatment plan was tested in patients recruited over 10 years from the UK, Mexico, India, Italy, and Brazil. Cervical cancer is the fourth most common cancer in women globally, with about 660,000 new cases and 350,000 deaths every year, according to the World Health Organization.

Virus up close

‘Gamechanger’ HIV prevention drug to be made available cheaply in 120 countries

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Gilead Sciences says it has signed agreements with six manufacturers to make and sell generic lenacapavir in 120 “high-incidence, resource-limited” countries. Lenacapavir, given as a twice-yearly injection, has shown strong results for HIV prevention. It stopped infection in a trial involving girls and women in South Africa and Uganda, and offered almost complete protection in a second trial that mainly involved men across Argentina, Brazil, Mexico, Peru, South Africa, Thailand, and the U.S.

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