Michelangelo begins painting frescoes on ceiling of the Sistine Chapel
The frescoes, which take up the entirety of the vault, are among the most important paintings in the world.
1500-1509 C.E.
Hieronymus Bosch paints “The Garden of Earthly Delights”
The Garden of Earthly Delights is considered Bosch’s seminal masterpiece and the most successful and outstanding of his creations.
Vasco da Gama becomes first European to discover Seychelles
On 15 March 1503, Vasco da Gama, crossing from India to East Africa, sighted what was almost certainly Silhouette Island and the next day, Desroches Island. The granitic islands began to appear on Portuguese charts as the Seven Sisters.
Rodrigo de Bastidas becomes the first European to explore the Isthmus of Panama
A year later Christopher Columbus on his fourth voyage, sailing south and eastward from upper Central America, explored Bocas del Toro, Veragua, the Chagres River and Portobelo (Beautiful Port) which he named.
Jacob Nufer of Switzerland performs the first known Cesarean Section birth with both mother and baby surviving
Perhaps the first written record we have of a mother and baby surviving a cesarean section comes from Switzerland in 1500 when sow gelder, Jacob Nufer, performed the operation on his wife. The mother lived and subsequently gave birth normally to five children, including twins. The cesarean baby lived to be 77 years old.