Science & academia

HIV virus

New twice-yearly shot to prevent HIV achieves 100% success rate in late-stage trial

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In this double-blind, randomized study of 5,300 cisgender women in South Africa and Uganda, 2,134 got the injection and the others took one of two types of daily PrEP pills. The trial from California-based company Gilead Sciences began on August 2021 and, so far, not a single woman who received the injections has contracted HIV. The participants who received either of the oral PrEP options, Truvada and Descovy, had infection rates of about 2% — consistent with the infection rates of oral PrEP in other clinical trials.

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Mouse

Japanese scientists reverse Alzheimer’s synapse damage in mice

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Scientists from the Okinawa Institute of Science and Technology say they have reversed the signs of Alzheimer’s disease in lab mice by restoring the healthy function of synapses, critical parts of neurons that shoot chemical messages to other neurons. If the treatment successfully survives the gauntlet of clinical studies with human participants, it could potentially lead to a groundbreaking new treatment for humans suffering from the deadly disease.

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Sick woman, stomach pain and hands on abdomen

U.K. researchers identify and treat major cause of inflammatory bowel disease

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For the first time, a major trigger in inflammatory bowel disease (IBD) and related conditions has been identified, and existing drugs can stamp it out, in what scientists call a “massive step” in successfully treating these debilitating chronic conditions. Researchers at the Francis Crick Institute, in collaboration with University College London (UCL) and Imperial College London (ICL), have uncovered a problem gene enhancer that stimulates action along a specific biological pathway that causes IBD inflammation.

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X-ray image of the intestine

New bowel cancer drug is found to be 100% effective

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An immunotherapy drug could spare bowel cancer patients the need for surgery and chemotherapy after results showed it was effective in 100% of cases. Jemperli from British pharmaceutical company GSK showed “unprecedented results”, the firm said, with no evidence of disease in all patients treated. The data showed all 42 patients in a trial led by Memorial Sloan Kettering Cancer Center in the U.S. had a complete response to treatment, with no evidence of tumors on scans.

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Holding breast cancer ribbon

New blood test can predict breast cancer return

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An “ultra-sensitive” new blood test developed and tested by Institute of Cancer Research (ICR) London can predict if breast cancer will return years before the disease shows up on scans, researchers say. It picks up traces of a tumor’s DNA before a full relapse and was found to be 100% accurate at predicting which patients would see their cancer return. It is hoped that the test can allow treatment to start earlier and improve survival rates.

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Car HUD

Chinese scientists discover way to make batteries more efficient

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A new water-based battery design is safer and more energy-efficient than traditional lithium-ion batteries, researchers from the Chinese Academy of Sciences claim. Today’s lithium batteries have enabled the rise of EVs, but their flammable organic electrolytes make them a fire risk, and their energy density puts a cap on EV driving range. The new water-based design replaces those combustible components with a safer, more stable water-based electrolyte that can pack way more energy into the same space.

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Cancer Cells under microscope

Thousands in the U.K. to trial breakthrough personalized cancer vaccines

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Under the new scheme from the U.K. National Health Service, the first of its kind in the world, patients who meet the eligibility criteria and agree to have a blood test and sample of their cancer tissue analyzed will gain immediate access to clinical trials for the new vaccines that experts say represent a new dawn of treatments for cancer. While research into cancer vaccines is at an early stage, trials have already shown they can be effective at killing off any remaining tumor cells after surgery and dramatically cut the risk of cancer returning.

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Cryo sauna for whole body cryotherapy

Cryo-cooling breakthrough slashes the energy cost of serious cold by 71%

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Cryogenic cooling is used to preserve tissues, eggs, sperm, and embryos and CAT scanners, CERN’s massive particle accelerators, and the James Webb Space Telescope possible. It may also one day be the key to making fusion power or quantum computers a reality. However, it is also quite energy-intensive. Fortunately, researchers at the U.S.’s National Institute of Standards & Technology have recently discovered a way to reach near-absolute zero up to 3.5 times faster or using about 71% less energy.

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Aral Sea time lapse 1989 2014

Uzbekistan plants millions of acres of forest where the Aral Sea once lay

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Instead of trying to restore what used to be the world’s third largest lake, officials from the Uzbekistan Forestry Agency and locals are trying to plant a new forest where it once rested. The main purpose of the afforestation project it to curb the harmful sandstorms and improve the ecosystem by planting desert-tolerant plants. The initiative has so far planted 4.2 million acres of forest, with up to 494,000 acres of new forest planned for 2024.

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Wooden satellite

Japanese scientists build world’s first wooden satellite

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The satellite dubbed LignoSat, a collaboration between Kyoto University and the company Sumitomo Forestry, is reportedly slated for launch in September onboard a SpaceX rocket. If successful, the tiny device — just four inches on each side — could represent a major breakthrough in space sustainability efforts. The idea is that it’ll burn up entirely upon reentry, vastly reducing its environmental impact compared to traditional metal spacecraft.

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